TMA-DPH

CAS No. 115534-33-3

TMA-DPH( —— )

Catalog No. M23334 CAS No. 115534-33-3

TMA-DPH is a hydrophobic fluorescent membrane probe (Ex: 355 nm; Em: 430 nm).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    TMA-DPH
  • Note
    Research use only, not for human use.
  • Brief Description
    TMA-DPH is a hydrophobic fluorescent membrane probe (Ex: 355 nm; Em: 430 nm).
  • Description
    TMA-DPH is a hydrophobic fluorescent membrane probe (Ex: 355 nm; Em: 430 nm).
  • In Vitro
    In contact with cells, TMA-DPH is instantaneously incorporated into the plasma membrane. TMA-DPH is concentrated in lysosomes and highly acidic late endosomes. The TMA-DPH fluorescence lifetime remains constant, 6.2±0.2 ns, below the same critical concentration of 2 μM, but decreases significantly with higher concentrations. This decrease, however, slows down above 5 μM. The TMA-DPH fluorescence anisotropy displays a similar evolution to the fluorescence lifetime. It is first constant, 0.283±0.003, again until 2 μM, and then decreases rapidly to 0.270±0.003 with 5 μM, continuing to fall, but at a lower rate with higher concentrations.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    115534-33-3
  • Formula Weight
    461.62
  • Molecular Formula
    C28H31NO3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 10 mg/mL (21.66 mM)
  • SMILES
    C[N+](C)(C)C1=CC=C(/C=C/C=C/C=C/C2=CC=CC=C2)C=C1.[O-]S(=O)(C3=CC=C(C)C=C3)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Illinger D, et al. The kinetic aspects of intracellular fluorescence labeling with TMA-DPH support the maturation model for endocytosis in L929 cells. J Cell Biol. 1994 May;125(4):783-94.
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