TLC2976-0103( —— )

Catalog No. M37683 CAS No. 692869-38-8

ROCK1-IN-1 is an inhibitor of ROCK1 with a K i value of 540 nM. ROCK1-IN-1 can be used in the research of hypertension, glaucoma and erectile dysfunction .

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

TLC2976-0103
Note

Research use only, not for human use.
Brief Description

ROCK1-IN-1 is an inhibitor of ROCK1 with a K i value of 540 nM. ROCK1-IN-1 can be used in the research of hypertension, glaucoma and erectile dysfunction .
Description

ROCK1-IN-1 is a ROCK1 inhibitor with a Ki value of 540 nM. ROCK1-IN-1 can be used for the research of hypertension, glaucoma and erectile dysfunction.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

692869-38-8
Formula Weight

325.38
Molecular Formula

C17H15N3O2S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (384.17 mM; Ultrasonic (<60°C)
SMILES

COc1ccc(CC(=O)Nc2nc(cs2)-c2ccncc2)cc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Green J, et al. Design, Synthesis, and Structure-Activity Relationships of Pyridine-Based Rho Kinase (ROCK) Inhibitors. J Med Chem. 2015 Jun 25;58(12):5028-37.?

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