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TINK-IN-1
CAS No. 1417795-25-5
TINK-IN-1( —— )
Catalog No. M37028 CAS No. 1417795-25-5
TINK-IN-1 is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 53 | Get Quote |
|
| 5MG | 75 | Get Quote |
|
| 10MG | 123 | Get Quote |
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| 25MG | 242 | Get Quote |
|
| 50MG | 361 | Get Quote |
|
| 100MG | 518 | Get Quote |
|
| 500MG | 1098 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameTINK-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionTINK-IN-1 is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation.
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DescriptionTINK-IN-1 (Compound 9) is a potent and selective Traf2- and Nck-interacting kinase (TNIK) inhibitor with an IC50 of 8 nM. TINK-IN-1 inhibits colorectal cancer cells viability.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayWnt/Notch/Hedgehog
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TargetWnt/beta/catenin
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RecptorWnt/beta-catenin
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Research Area——
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Indication——
Chemical Information
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CAS Number1417795-25-5
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Formula Weight416.47
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Molecular FormulaC24H24N4O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (300.14 mM; Ultrasonic )
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SMILESN#CC=1C=CC(OC)=C(C1)C=2C=CN=C(C2)NC3=CC=C(C(OC)=C3)N4CCOCC4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ho KK, et al. Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. Bioorg Med Chem Lett. 2013 Jan 15;23(2):569-73.?
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