TFMB-(R)-2-HG

CAS No. 1445700-01-5

TFMB-(R)-2-HG ( —— )

Catalog No. M23608 CAS No. 1445700-01-5

TFMB-(R)-2-HG is a carcinogenic factor in Acute myeloid leukemia (AML). TFMB-(R)-2-HG impairs SCF ER-Hoxb8 cell differentiation in response to estrogen withdrawal.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 88 In Stock
5MG 152 In Stock
10MG 237 In Stock
25MG 441 In Stock
50MG 651 In Stock
100MG 888 In Stock
500MG 1782 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    TFMB-(R)-2-HG
  • Note
    Research use only, not for human use.
  • Brief Description
    TFMB-(R)-2-HG is a carcinogenic factor in Acute myeloid leukemia (AML). TFMB-(R)-2-HG impairs SCF ER-Hoxb8 cell differentiation in response to estrogen withdrawal.
  • Description
    TFMB-(R)-2-HG is a carcinogenic factor in Acute myeloid leukemia (AML). TFMB-(R)-2-HG impairs SCF ER-Hoxb8 cell differentiation in response to estrogen withdrawal.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Carcinogenic factor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1445700-01-5
  • Formula Weight
    288.2
  • Molecular Formula
    C13H11F3O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:240 mg/mL (832.7 mM)
  • SMILES
    O=C([C@@H](CC1)OC1=O)OCC2=CC=CC(C(F)(F)F)=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Losman JA, et al. (R)-2-hydroxyglutarate is sufficient to promote leukemogenesis and its effects are reversible. Science. 2013 Mar 29;339(6127):1621-5.
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