TFMB-(R)-2-HG( —— )

Catalog No. M23608 CAS No. 1445700-01-5

TFMB-(R)-2-HG is a carcinogenic factor in Acute myeloid leukemia (AML). TFMB-(R)-2-HG impairs SCF ER-Hoxb8 cell differentiation in response to estrogen withdrawal.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

TFMB-(R)-2-HG
Note

Research use only, not for human use.
Brief Description

TFMB-(R)-2-HG is a carcinogenic factor in Acute myeloid leukemia (AML). TFMB-(R)-2-HG impairs SCF ER-Hoxb8 cell differentiation in response to estrogen withdrawal.
Description

TFMB-(R)-2-HG is a carcinogenic factor in Acute myeloid leukemia (AML). TFMB-(R)-2-HG impairs SCF ER-Hoxb8 cell differentiation in response to estrogen withdrawal.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Carcinogenic factor
Research Area

——
Indication

——

Chemical Information

CAS Number

1445700-01-5
Formula Weight

288.22
Molecular Formula

C13H11F3O4
Purity

>98% (HPLC)
Solubility

DMSO:240 mg/mL (832.7 mM)
SMILES

O=C([C@@H](CC1)OC1=O)OCC2=CC=CC(C(F)(F)F)=C2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Losman JA, et al. (R)-2-hydroxyglutarate is sufficient to promote leukemogenesis and its effects are reversible. Science. 2013 Mar 29;339(6127):1621-5.

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