TCID ( UCH-L3 Inhibitor )

Catalog No. M13979 CAS No. 30675-13-9

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Datasheet

HNMR

HPLC

MSDS

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Product Name

TCID
Note

Research use only, not for human use.
Brief Description

TCID is a selective ubiquitin C-terminal hydrolase-L3 (UCH-L3) inhibitor with IC50 of 0.6 uM.
Description

TCID is a selective ubiquitin C-terminal hydrolase-L3 (UCH-L3) inhibitor with IC50 of 0.6 uM, displays >100-fold selectivity over UCH-L1; diminishes glycine transporter GlyT2 ubiquitination in brain stem and spinal cord primary neurons.
Synonyms

UCH-L3 Inhibitor
Pathway

Proteasome/Ubiquitin
Target

DUB
Recptor

UCH-L1;UCH-L3
Research Area

Other Indications
Indication

——

CAS Number

30675-13-9
Formula Weight

283.90
Molecular Formula

C9H2Cl4O2
Purity

>98% (HPLC)
Solubility

DMSO: 14.2 mg/mL (50 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble )
SMILES

C1C(=O)C2=C(C1=O)C(=C(C(=C2Cl)Cl)Cl)Cl
Chemical Name

4,5,6,7-Tetrachloro-1H-Indene-1,3(2H)-dione

1. Liu Y, et al. Chem Biol. 2003 Sep;10(9):837-46.
2. de Juan-Sanz J, et al. PLoS One. 2013;8(3):e58863.

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