TBOPP
CAS No. 1996629-79-8
TBOPP ( —— )
Catalog No. M22123 CAS No. 1996629-79-8
TBOPP is a selective DOCK1 inhibitor (IC50 : 8.4 μM), with anti-tumor activity for broader types of tumors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 336 | In Stock |
|
10MG | 426 | In Stock |
|
25MG | 699 | In Stock |
|
50MG | 981 | In Stock |
|
100MG | 1314 | In Stock |
|
500MG | 2637 | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameTBOPP
-
NoteResearch use only, not for human use.
-
Brief DescriptionTBOPP is a selective DOCK1 inhibitor (IC50 : 8.4 μM), with anti-tumor activity for broader types of tumors.
-
DescriptionTBOPP is a selective DOCK1 inhibitor (IC50 : 8.4 μM), with anti-tumor activity for broader types of tumors. TBOPP as a selective inhibitor of DOCK1.?TBOPP dampened DOCK1-mediated invasion, macropinocytosis, and survival under the condition of glutamine deprivation without impairing the biological functions of the closely related DOCK2 and DOCK5 proteins.TBOPP treatment suppressed cancer metastasis and growth in vivo in mice.
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorDOCK1;DOCK1 DHR-2 domain
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1996629-79-8
-
Formula Weight490.49
-
Molecular FormulaC24H21F3N2O4S
-
Purity>98% (HPLC)
-
SolubilityDMSO:120 mg/mL (244.65 mM; Need ultrasonic)
-
SMILESFC(F)(F)c1cccc(c1)-c1ccc(cc1)C(=O)Cn1cc(ccc1=O)S(=O)(=O)N1CCCC1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Tajiri H, et al. Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCKCell Rep. 2017 May 2;19(5):969-980.
molnova catalog
related products
-
Ponceau S
Ponceau S (Acid Red 112) is the most commonly used stain for Western blotting binding with antibody-antigen, and stains the proteins on the membrane red.
-
Cilazapril Monohydra...
Cilazapril Monohydrate is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.
-
Picraquassioside B
The herbs of Senecio solidagineus.