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TB5

CAS No. 948841-07-4

TB5 ( TB5, TB 5, TB-5 )

Catalog No. M17687 CAS No. 948841-07-4

TB5 is a potent, selective and reversible inhibitor of hMAO-B.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 59 In Stock
25MG 109 In Stock
50MG 177 In Stock
100MG 284 In Stock
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Biological Information

  • Product Name
    TB5
  • Note
    Research use only, not for human use.
  • Brief Description
    TB5 is a potent, selective and reversible inhibitor of hMAO-B.
  • Description
    TB5 is a MAO-B inhibitor. TB5 showed the inhibitory activity and selectivity toward hMAO-B, with Ki and SI values of 0.11±0.01μm and 13.18, respectively. TB5 was found to be nontoxic at 5 and 25μm, with 95.75 and 84.59% viability among cells, respectively.
  • Synonyms
    TB5, TB 5, TB-5
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    hMAO-B
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    948841-07-4
  • Formula Weight
    336.25
  • Molecular Formula
    C15H14BrNOS
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    CN(C)c1ccc(cc1)/C=C/C(=O)c1ccc(s1)Br
  • Chemical Name
    (2E)-1-(5-bromothiophen-2-yl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Mathew B, et al. Synthesis, Biochemistry, and Computational Studies of Brominated Thienyl Chalcones: A New Class of Reversible MAO-B Inhibitors. ChemMedChem. 2016 Jun 6;11(11):1161-71.
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