TB5

CAS No. 948841-07-4

TB5 ( TB5, TB 5, TB-5 )

Catalog No. M17687 CAS No. 948841-07-4

TB5 is a potent, selective and reversible inhibitor of hMAO-B.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 37 In Stock
10MG 59 In Stock
25MG 109 In Stock
50MG 177 In Stock
100MG 284 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    TB5
  • Note
    Research use only, not for human use.
  • Brief Description
    TB5 is a potent, selective and reversible inhibitor of hMAO-B.
  • Description
    TB5 is a MAO-B inhibitor. TB5 showed the inhibitory activity and selectivity toward hMAO-B, with Ki and SI values of 0.11±0.01μm and 13.18, respectively. TB5 was found to be nontoxic at 5 and 25μm, with 95.75 and 84.59% viability among cells, respectively.
  • Synonyms
    TB5, TB 5, TB-5
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    hMAO-B
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    948841-07-4
  • Formula Weight
    336.25
  • Molecular Formula
    C15H14BrNOS
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    CN(C)c1ccc(cc1)/C=C/C(=O)c1ccc(s1)Br
  • Chemical Name
    (2E)-1-(5-bromothiophen-2-yl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Mathew B, et al. Synthesis, Biochemistry, and Computational Studies of Brominated Thienyl Chalcones: A New Class of Reversible MAO-B Inhibitors. ChemMedChem. 2016 Jun 6;11(11):1161-71.
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