TAK-981( Subasumstat )

Catalog No. M23846 CAS No. 1858276-04-6

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

TAK-981
Note

Research use only, not for human use.
Brief Description

TAK-981 is a selective the SUMOylation enzymatic cascade inhibitor, has potential immune-activating and antineoplastic activities.
Description

TAK-981 is a selective the SUMOylation enzymatic cascade inhibitor, has potential immune-activating and antineoplastic activities. (In Vitro):Subasumstat (TAK-981) is able to increase the production of type 1 IFN, thereby increasing type 1 IFN-mediated signaling, activating innate effector cells and enhancing the antitumor innate immune responses.(In Vivo):A single sub-cutaneous injection of Subasumstat (TAK-981) in naive Balb/c mice at the brachial lymph nodes induces activation of DCs.
In Vitro

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In Vivo

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Synonyms

Subasumstat
Pathway

Others
Target

Other Targets
Recptor

SUMOylation
Research Area

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Indication

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CAS Number

1858276-04-6
Formula Weight

578.1
Molecular Formula

C25H28ClN5O5S2
Purity

>98% (HPLC)
Solubility

DMSO:75 mg/mL (129.74 mM; Need ultrasonic)
SMILES

Cc1c([C@@H]2NCCc(cc3)c2cc3Cl)cc(C(c2c(N[C@H](C[C@@H]3COS(N)(=O)=O)C[C@@H]3O)ncnc2)=O)s1
Chemical Name

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