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Suprafenacine

CAS No. 1477482-50-0

Suprafenacine( N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide )

Catalog No. M27928 CAS No. 1477482-50-0

Suprafenacine is a cell-permeable microtubule destabilizer that induces cell cycle arrest and apoptosis in G2/M phase.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Suprafenacine
  • Note
    Research use only, not for human use.
  • Brief Description
    Suprafenacine is a cell-permeable microtubule destabilizer that induces cell cycle arrest and apoptosis in G2/M phase.
  • Description
    Suprafenacine is a cell-permeable microtubule destabilizer that induces cell cycle arrest and apoptosis in G2/M phase. Suprafenacine binds to microtubules and inhibits aggregation at the colchicine junction. Suprafenacine is selective for cancer cells, including drug-resistant cancer cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Microtubule/Tubulin
  • Recptor
    β2-adrenergic receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1477482-50-0
  • Formula Weight
    282.347
  • Molecular Formula
    C16H18N4O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cc1ccc(\C=N\NC(=O)c2n[nH]c3CCCCc23)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Shuyun Bi, et al. Study on the interactions of mapenterol with serum albumins using multi-spectroscopy and molecular docking. Luminescence. 2016 Mar;31(2):372-379.
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