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Sovilnesib

CAS No. 2410796-79-9

Sovilnesib( AMG 650 )

Catalog No. M28250 CAS No. 2410796-79-9

Sovilnesib is a kinesin-like protein KIF18A inhibitor (WO2020132648). Sovilnesib can be used for the research of cancer.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 222 Get Quote
10MG 356 Get Quote
25MG 597 Get Quote
50MG 851 Get Quote
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Biological Information

  • Product Name
    Sovilnesib
  • Note
    Research use only, not for human use.
  • Brief Description
    Sovilnesib is a kinesin-like protein KIF18A inhibitor (WO2020132648). Sovilnesib can be used for the research of cancer.
  • Description
    Sovilnesib is a kinesin-like protein KIF18A inhibitor (WO2020132648). Sovilnesib can be used for the research of cancer.(In Vitro):Sovilnesib is a kinesin-like protein KIF18A inhibitor.
  • In Vitro
    Cell Viability Assay Cell Line:Cancer cell lines Concentration:0-10 pM Incubation Time:96 and 144 hours Result:Inhibited tumor cell growth in a dose-dependent manner.
  • In Vivo
    Animal Model:Female nude mice without thymus with OVCAR-3 xenografts Dosage:10, 30, and 100 mg/kg Administration:Oral administration; daily, for 45 days Result:Had antitumor efficacy in a dose-dependent manner.
  • Synonyms
    AMG 650
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Microtubule/Tubulin
  • Recptor
    Histamine relase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2410796-79-9
  • Formula Weight
    564.65
  • Molecular Formula
    C26H34F2N6O4S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (177.10 mM)
  • SMILES
    Cc1cc(NC(c(ccc(NS(CCO)(=O)=O)c2)c2N2CCC3(CC3)CC2)=O)nc(N(CC2)CCC2(F)F)n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Watt GD, et al. Protective effect opf lodoxamide tromethamine on allergen inhalation challenge. J Allergy Clin Immunol. 1980 Oct;66(4):286-94.
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