Sulfathiazole

CAS No. 72-14-0

Sulfathiazole( HSDB4380 | HSDB-4380 | HSDB 4380 | Sulfathiazole | Planomide | Poliseptil )

Catalog No. M15758 CAS No. 72-14-0

Sulfathiazole is an organosulfur compound that has been used as a short-acting sulfa drug.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Sulfathiazole
  • Note
    Research use only, not for human use.
  • Brief Description
    Sulfathiazole is an organosulfur compound that has been used as a short-acting sulfa drug.
  • Description
    Sulfathiazole is an organosulfur compound that has been used as a short-acting sulfa drug.(In Vitro):Sulfathiazole (20 μg/L) starts to be degraded between day 31 and day 38 in one of the two batch reactors containing different wastewater matrices. Sulfathiazole is degraded at a substantially faster rate than sulfamethoxazole or sulfamethazine in the nitrification process (S3). Recovery from spiked manure slurry samples is 64% for Sulfathiazole at pH 9. Sulfathiazole has acidity constant of pKa of 7.1and retention times (tR) of 7.8. S/N values for Sulfathiazole are above 100 at the 1 mg/kg level]. Sulfathiazole sorption to inorganic sorbents exhibits pronounced pH dependence consistent with sorbate speciation and sorbent charge properties. Sulfathiazole cations are most important for sorption to clay minerals, followed by neutral species.
  • In Vitro
    Sulfathiazole (20 μg/L) starts to be degraded between day 31 and day 38 in one of the two batch reactors containing different wastewater matrices. Sulfathiazole is degraded at a substantially faster rate than sulfamethoxazole or sulfamethazine in the nitrification process (S3). Recovery from spiked manure slurry samples is 64% for Sulfathiazole at pH 9. Sulfathiazole has acidity constant of pKa of 7.1and retention times (tR) of 7.8. S/N values for Sulfathiazole are above 100 at the 1 mg/kg level]. Sulfathiazole sorption to inorganic sorbents exhibits pronounced pH dependence consistent with sorbate speciation and sorbent charge properties. Sulfathiazole cations are most important for sorption to clay minerals, followed by neutral species.
  • In Vivo
    ——
  • Synonyms
    HSDB4380 | HSDB-4380 | HSDB 4380 | Sulfathiazole | Planomide | Poliseptil
  • Pathway
    Autophagy
  • Target
    Autophagy
  • Recptor
    DHPS| DHPS
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    72-14-0
  • Formula Weight
    255.32
  • Molecular Formula
    C9H9N3O2S2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 51 mg/mL (199.74 mM)
  • SMILES
    O=S(NC1=NC=CS1)(C2=CC=C(N)C=C2)=O
  • Chemical Name
    4-amino-N-(thiazol-2-yl)benzenesulfonamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Nichols BP, Guay GG. Antimicrob Agents ChemOthers. 1989 Dec;33(12):2042-8.
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