Cart
sales@molnova.com
Home - Products - Autophagy - Autophagy - STF-62247

STF-62247

CAS No. 315702-99-9

STF-62247 ( STF62247;STF 62247 )

Catalog No. M14025 CAS No. 315702-99-9

STF-62247 is a small molecule Autophagy inducer that induces autophagy and selectively induces lethality in VHL-deficient RCC cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 28 In Stock
10MG 41 In Stock
25MG 88 In Stock
50MG 153 In Stock
100MG 267 In Stock
200MG 411 In Stock
500MG 664 In Stock
1G Get Quote In Stock
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    STF-62247
  • Note
    Research use only, not for human use.
  • Brief Description
    STF-62247 is a small molecule Autophagy inducer that induces autophagy and selectively induces lethality in VHL-deficient RCC cells.
  • Description
    STF-62247 is a small molecule Autophagy inducer that induces autophagy and selectively induces lethality in VHL-deficient RCC cells; induces cytotoxicity and reduces tumor growth in VHL-deficient cells in a HIF-independent manner, PI3K and Golgi trafficking are required as initial signals in STF-62247-induced autophagy.Kidney Cancer Preclinical
  • Synonyms
    STF62247;STF 62247
  • Pathway
    Autophagy
  • Target
    Autophagy
  • Recptor
    ER
  • Research Area
    Cancer
  • Indication
    Kidney Cancer

Chemical Information

  • CAS Number
    315702-99-9
  • Formula Weight
    267.35
  • Molecular Formula
    C15H13N3S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 31 mg/mL
  • SMILES
    CC1=CC(NC2=NC(C3=CC=NC=C3)=CS2)=CC=C1
  • Chemical Name
    2-Thiazolamine, N-(3-methylphenyl)-4-(4-pyridinyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Turcotte S, et al. Cancer Cell. 2008 Jul 8;14(1):90-102.
2. Turcotte S, et al. Autophagy. 2008 Oct;4(7):944-6.
3. Chan DA, et al. Cell Cycle. 2008 Oct;7(19):2987-90.
4.Kozako T, et al. Oncotarget. 2018 Jun 12;9(45):27645-27655.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Ginkgolide K

    Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity.

  • Glycycoumarin

    Glycycoumarin is an estrogen agonist, it shows moderate inhibitory effects against CYP1A2 and CYP2B6.

  • Corynoxine hydrochlo...

    Corynoxine is a natural oxindole alkaloid and induces autophagy in different neuronal cell lines including N2a and SHSY-5Y cells.

Sign In Join Free