Sulfaguanidine

CAS No. 57-67-0

Sulfaguanidine( Sulfaguanidine | Ganidan )

Catalog No. M15106 CAS No. 57-67-0

Sulfaguanidine is a sulfonamide used as an anti-infective agent.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Sulfaguanidine
  • Note
    Research use only, not for human use.
  • Brief Description
    Sulfaguanidine is a sulfonamide used as an anti-infective agent.
  • Description
    Sulfaguanidine is a sulfonamide used as an anti-infective agent.(In Vivo):Sulfaguanidine (2.5 mg/kg; i.v.) exhibits CLt (adult 0.29, neonate 0.14 L/h/kg), AUC0-∞ (adult 8.18, neonate 20.46 μg?h/mL), and Vdss (adult 0.65, neonate 0.59 L/kg) in rats.Sulfaguanidine (2.5 mg/kg; p.o.) exhibits absolute bioavailability (adult 12.76%, neonate 57.86%), Cmax (adult 0.41, neonate 3.56 μg/mL), and Tmax (adult 1.67, neonate 1.50 h) in rats.
  • In Vitro
    ——
  • In Vivo
    Sulfaguanidine (2.5 mg/kg; i.v.) exhibits CLt (adult 0.29, neonate 0.14 L/h/kg), AUC0-∞ (adult 8.18, neonate 20.46 μg?h/mL), and Vdss (adult 0.65, neonate 0.59 L/kg) in rats.Sulfaguanidine (2.5 mg/kg; p.o.) exhibits absolute bioavailability (adult 12.76%, neonate 57.86%), Cmax (adult 0.41, neonate 3.56 μg/mL), and Tmax (adult 1.67, neonate 1.50 h) in rats.
  • Synonyms
    Sulfaguanidine | Ganidan
  • Pathway
    Autophagy
  • Target
    Autophagy
  • Recptor
    DHPS
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    57-67-0
  • Formula Weight
    214.25
  • Molecular Formula
    C7H10N4O2S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 43 mg/mL (200.7 mM)
  • SMILES
    O=S(C1=CC=C(N)C=C1)(NC(N)=N)=O
  • Chemical Name
    Benzenesulfonamide, 4-amino-N-(aminoiminomethyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Mizuno N, et al. J Pharmacobiodyn. 1986, 9(10), 787-792.
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