Sucralose( —— )

Catalog No. M15040 CAS No. 56038-13-2

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HPLC

MSDS

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Product Name

Sucralose
Note

Research use only, not for human use.
Brief Description

Sucralose is an artificial and noncaloric sweetener, not broken down by the body, so it is noncaloric.
Description

Sucralose is an artificial and noncaloric sweetener, not broken down by the body, so it is noncaloric.(In Vitro):The results show that Sucralose induces significant increased incidence of all hematopoietic neoplasias in male mice exposed to 2,000 (p≤0.01), and 16,000 ppm (p≤0.01), with a significant dose-related relationship (p≤0.01). Microscopically, most of the neoplasias among male mice treated with Sucralose at 2,000 to 16,000 ppm are leukemias involving lungs, liver, spleen, lymph nodes, and bone marrow with diffuse permeation of vessels and extensive infiltration of adjacent tissues.
In Vitro

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In Vivo

The results show that Sucralose induces significant increased incidence of all hematopoietic neoplasias in male mice exposed to 2,000 (p≤0.01), and 16,000 ppm (p≤0.01), with a significant dose-related relationship (p≤0.01). Microscopically, most of the neoplasias among male mice treated with Sucralose at 2,000 to 16,000 ppm are leukemias involving lungs, liver, spleen, lymph nodes, and bone marrow with diffuse permeation of vessels and extensive infiltration of adjacent tissues.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Other Indications
Indication

——

CAS Number

56038-13-2
Formula Weight

397.63
Molecular Formula

C12H19Cl3O8
Purity

>98% (HPLC)
Solubility

Water: 80 mg/mL (201.19 mM); DMSO: 80 mg/mL (201.19 mM)
SMILES

C([C@@H]1[C@@H]([C@@H]([C@H]([C@H](O1)O[C@]2([C@H]([C@@H]([C@H](O2)CCl)O)O)CCl)O)O)Cl)O
Chemical Name

——

1.Stoddard KI, Huggett DB. Bull Environ Contam Toxicol. 2014 Oct;93(4):383-7.

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