Solithromycin
CAS No. 760981-83-7
Solithromycin ( CEM-101;OP-1068 )
Catalog No. M15888 CAS No. 760981-83-7
A novel fluoroketolide with lower MICs than those of telithromycin and macrolides.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 29 | In Stock |
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5MG | 46 | In Stock |
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10MG | 80 | In Stock |
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25MG | 160 | In Stock |
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50MG | 264 | In Stock |
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100MG | Get Quote | In Stock |
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200MG | Get Quote | In Stock |
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500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameSolithromycin
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NoteResearch use only, not for human use.
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Brief DescriptionA novel fluoroketolide with lower MICs than those of telithromycin and macrolides.
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DescriptionA novel fluoroketolide with lower MICs than those of telithromycin and macrolides; binds to the large 50S subunit of the ribosome and inhibits protein biosynthesis; exhibits MICs of 7.5, 40, and 125 ng/ml for Streptococcus pneumoniae,Staphylococcus aureus, and Haemophilus influenzae, respectively. Bacterial Infection Approved
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SynonymsCEM-101;OP-1068
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibiotic
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Research AreaInfection
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IndicationBacterial Infection
Chemical Information
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CAS Number760981-83-7
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Formula Weight845.01
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Molecular FormulaC43H65FN6O10
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 32 mg/mL
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SMILESCC[C@@H]1[C@@]2([C@@H]([C@@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H](C(=O)[C@@](C(=O)O1)(C)F)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)OC)C)C)N(C(=O)O2)CCCCN4C=C(N=N4)C5=CC(=CC=C5)N)C
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Chemical Name2H-Oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)-tetrone, 1-[4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl]-4-ethyl-7-fluorooctahydro-11-methoxy-3a,7,9,11,13,15-hexamethyl-10-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (3aS,
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Waites KB, et al. Antimicrob Agents Chemother. 2009 May;53(5):2139-41.
2. Lemaire S, et al. Antimicrob Agents Chemother. 2009 Sep;53(9):3734-43.
3. Roblin PM, et al. Antimicrob Agents Chemother. 2010 Mar;54(3):1358-9.
2. Lemaire S, et al. Antimicrob Agents Chemother. 2009 Sep;53(9):3734-43.
3. Roblin PM, et al. Antimicrob Agents Chemother. 2010 Mar;54(3):1358-9.
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