Solithromycin

CAS No. 760981-83-7

Solithromycin ( CEM-101;OP-1068 )

Catalog No. M15888 CAS No. 760981-83-7

A novel fluoroketolide with lower MICs than those of telithromycin and macrolides.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 29 In Stock
5MG 46 In Stock
10MG 80 In Stock
25MG 160 In Stock
50MG 264 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    Solithromycin
  • Note
    Research use only, not for human use.
  • Brief Description
    A novel fluoroketolide with lower MICs than those of telithromycin and macrolides.
  • Description
    A novel fluoroketolide with lower MICs than those of telithromycin and macrolides; binds to the large 50S subunit of the ribosome and inhibits protein biosynthesis; exhibits MICs of 7.5, 40, and 125 ng/ml for Streptococcus pneumoniae,Staphylococcus aureus, and Haemophilus influenzae, respectively. Bacterial Infection Approved
  • Synonyms
    CEM-101;OP-1068
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibiotic
  • Research Area
    Infection
  • Indication
    Bacterial Infection

Chemical Information

  • CAS Number
    760981-83-7
  • Formula Weight
    845.01
  • Molecular Formula
    C43H65FN6O10
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 32 mg/mL
  • SMILES
    CC[C@@H]1[C@@]2([C@@H]([C@@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H](C(=O)[C@@](C(=O)O1)(C)F)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)OC)C)C)N(C(=O)O2)CCCCN4C=C(N=N4)C5=CC(=CC=C5)N)C
  • Chemical Name
    2H-Oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)-tetrone, 1-[4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl]-4-ethyl-7-fluorooctahydro-11-methoxy-3a,7,9,11,13,15-hexamethyl-10-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (3aS,

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Waites KB, et al. Antimicrob Agents Chemother. 2009 May;53(5):2139-41.
2. Lemaire S, et al. Antimicrob Agents Chemother. 2009 Sep;53(9):3734-43.
3. Roblin PM, et al. Antimicrob Agents Chemother. 2010 Mar;54(3):1358-9.
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