Shikonin

CAS No. 54952-43-1

Shikonin( (+-)-Alkannin, (+-)-Shikonin, Arnebin-4, Shikonin )

Catalog No. M14984 CAS No. 54952-43-1

Alkannin is a natural dye that is obtained from the extracts of plants from the borage family Alkanna tinctoria that are found in the south of France.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Shikonin
  • Note
    Research use only, not for human use.
  • Brief Description
    Alkannin is a natural dye that is obtained from the extracts of plants from the borage family Alkanna tinctoria that are found in the south of France.
  • Description
    Alkannin is a natural dye that is obtained from the extracts of plants from the borage family Alkanna tinctoria that are found in the south of France. The dye is used as a food coloring and in cosmetics. It is used as a red-brown food additive in regions such as Australia.
  • In Vitro
    Shikonin shows a similar potency toward drug-sensitive cancer cell lines (MCF-7 and HEK293) and their drug-resistant lines overexpressing P-glycoprotein, Bcl-2, or Bcl-xL, which account for most of the clinical cancer drug resistance.
  • In Vivo
    ——
  • Synonyms
    (+-)-Alkannin, (+-)-Shikonin, Arnebin-4, Shikonin
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    54952-43-1
  • Formula Weight
    288.29
  • Molecular Formula
    C16H16O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    CC(=CCC(C1=CC(=O)c2c(ccc(c2C1=O)O)O)O)C
  • Chemical Name
    1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)- (9CI)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhao Q, et al. Int J Y. 2015 Sep 15;137(6):1446-56.
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