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Shield-1
CAS No. 914805-33-7
Shield-1 ( —— )
Catalog No. M24959 CAS No. 914805-33-7
Shield-1 is a specific, high-affinity and cell-permeant ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused proteins. Shield-1 can stabilize the entire fusion protein.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 335 | In Stock |
|
| 10MG | 533 | In Stock |
|
| 25MG | 847 | In Stock |
|
| 50MG | 1152 | In Stock |
|
| 100MG | 1548 | In Stock |
|
| 500MG | 3087 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameShield-1
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NoteResearch use only, not for human use.
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Brief DescriptionShield-1 is a specific, high-affinity and cell-permeant ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused proteins. Shield-1 can stabilize the entire fusion protein.
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DescriptionShield-1 is a specific, high-affinity and cell-permeant ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused proteins. Shield-1 can stabilize the entire fusion protein.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorFKBP
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Research Area——
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Indication——
Chemical Information
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CAS Number914805-33-7
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Formula Weight748.9
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Molecular FormulaC42H56N2O10
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Purity>98% (HPLC)
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SolubilityDMSO:250 mg/mL (333.82 mM)
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SMILESO=C([C@H]1N(C([C@H](C2=CC(OC)=C(OC)C(OC)=C2)CC)=O)CCCC1)O[C@@H](C3=CC=CC(OCCN4CCOCC4)=C3)CCC5=CC=C(OC)C(OC)=C5
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Schoeber JP, et al. Conditional fast expression and function of multimeric TRPV5 channels using Shield-1. Am J Physiol Renal Physiol. 2009 Jan;296(1):F204-11.
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