alpha-Naphthoflavone

CAS No. 604-59-1

alpha-Naphthoflavone( —— )

Catalog No. M18879 CAS No. 604-59-1

Alpha-Naphthoflavone, a synthetic flavonoid, is a potent inhibitor of aromatase with an I50 value of 0.5 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 40 In Stock
5MG 37 In Stock
10MG 54 In Stock
25MG 89 In Stock
50MG 128 In Stock
100MG 194 In Stock
200MG Get Quote In Stock
500MG 551 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    alpha-Naphthoflavone
  • Note
    Research use only, not for human use.
  • Brief Description
    Alpha-Naphthoflavone, a synthetic flavonoid, is a potent inhibitor of aromatase with an I50 value of 0.5 μM.
  • Description
    Alpha-Naphthoflavone, a synthetic flavonoid, is a potent inhibitor of aromatase with an I50 value of 0.5 μM.
  • In Vitro
    Cell Proliferation Assay Cell Line:HeLa Concentration:0.01, 1, 10, 100 μM Incubation Time:6 days Result:Decreased cell proliferation in a dose-dependent manner with IC50 value of 36.81 μM.Apoptosis Analysis Cell Line:HeLa Concentration:50 μM Incubation Time:12, 24, 36 h Result:Induced a mild but significant apoptosis rate.Western Blot Analysis Cell Line:HeLa Concentration:50 μM Incubation Time:12, 24, 36 h Result:Increased the level of p53 at 12 h.
  • In Vivo
    Animal Model:HFD-induced mice model Dosage:80, 160 mg/kg Administration:i.g.Result:Decreased the levels of AST, TG and TC.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Aromatase
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    604-59-1
  • Formula Weight
    272.3
  • Molecular Formula
    C19H12O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (91.81 mM)
  • SMILES
    C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C4=CC=CC=C4C=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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