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Scoparone

CAS No. 120-08-1

Scoparone( Aesculetin dimethyl ether | 6,7-Dimethoxycoumarin | 6,7-Dimethylesculetin | Escoparone )

Catalog No. M10722 CAS No. 120-08-1

Extracted from A.scoparia Waldst.e Kit seeds;Store the product in sealed, cool and dry condition.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Scoparone
  • Note
    Research use only, not for human use.
  • Brief Description
    Extracted from A.scoparia Waldst.e Kit seeds;Store the product in sealed, cool and dry condition.
  • Description
    Extracted from A.scoparia Waldst.e Kit seeds;Store the product in sealed, cool and dry condition.(In Vitro):Scoparone (0-0.4 nM; 24-48 hours) produces the most inhibition on PSC proliferation at 0.4 nM.(In Vivo):Scoparone (oral administration; 30 mg/kg, 60 mg/kg; 4 weeks) greatly ameliorates the pancreatic weight loss induced by DBTC in pancreatitis rats.
  • In Vitro
    Scoparone (0-0.4 nM; 24-48 hours) produces the most inhibition on PSC proliferation at 0.4 nM.
  • In Vivo
    Scoparone (oral administration; 30 mg/kg, 60 mg/kg; 4 weeks) greatly ameliorates the pancreatic weight loss induced by DBTC in pancreatitis rats. Animal Model:Chronic Pancreatitis (CP) Rat Models Dosage:30 mg/kg, 60 mg/kg Administration:Oral administration; 30 mg/kg, 60 mg/kg; 4 weeks Result:Protected against pancreatic damage.
  • Synonyms
    Aesculetin dimethyl ether | 6,7-Dimethoxycoumarin | 6,7-Dimethylesculetin | Escoparone
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    120-08-1
  • Formula Weight
    206.2
  • Molecular Formula
    C11H10O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    O=C1C=CC2=CC(OC)=C(OC)C=C2O1
  • Chemical Name
    6,7-Dimethoxy-2-benzopyrone

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lee SH, Jang HD. Exp Cell Res. 2015 Feb 15;331(2):267-77.
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