Scoparone( Aesculetin dimethyl ether | 6,7-Dimethoxycoumarin | 6,7-Dimethylesculetin | Escoparone )

Catalog No. M10722 CAS No. 120-08-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Scoparone
Note

Research use only, not for human use.
Brief Description

Extracted from A.scoparia Waldst.e Kit seeds;Store the product in sealed, cool and dry condition.
Description

Extracted from A.scoparia Waldst.e Kit seeds;Store the product in sealed, cool and dry condition.(In Vitro):Scoparone (0-0.4 nM; 24-48 hours) produces the most inhibition on PSC proliferation at 0.4 nM.(In Vivo):Scoparone (oral administration; 30 mg/kg, 60 mg/kg; 4 weeks) greatly ameliorates the pancreatic weight loss induced by DBTC in pancreatitis rats.
In Vitro

Scoparone (0-0.4 nM; 24-48 hours) produces the most inhibition on PSC proliferation at 0.4 nM.
In Vivo

Scoparone (oral administration; 30 mg/kg, 60 mg/kg; 4 weeks) greatly ameliorates the pancreatic weight loss induced by DBTC in pancreatitis rats. Animal Model:Chronic Pancreatitis (CP) Rat Models Dosage:30 mg/kg, 60 mg/kg Administration:Oral administration; 30 mg/kg, 60 mg/kg; 4 weeks Result:Protected against pancreatic damage.
Synonyms

Aesculetin dimethyl ether | 6,7-Dimethoxycoumarin | 6,7-Dimethylesculetin | Escoparone
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Other Indications
Indication

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1.Lee SH, Jang HD. Exp Cell Res. 2015 Feb 15;331(2):267-77.

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