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Sardomozide
CAS No. 138794-73-7
Sardomozide( CGP 48664 dihydrochloride )
Catalog No. M28369 CAS No. 138794-73-7
Sardomozide is an inhibitor of S-adenosylmethionine decarboxylase (SAMDC, IC50 = 5 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 102 | Get Quote |
|
| 10MG | 177 | Get Quote |
|
| 25MG | 300 | Get Quote |
|
| 50MG | 447 | Get Quote |
|
| 100MG | 624 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameSardomozide
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NoteResearch use only, not for human use.
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Brief DescriptionSardomozide is an inhibitor of S-adenosylmethionine decarboxylase (SAMDC, IC50 = 5 nM).
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DescriptionSardomozide is an inhibitor of S-adenosylmethionine decarboxylase (SAMDC, IC50 = 5 nM).(In Vitro):In CHO/664 cells treated with DENSPM, Sardomozide inhibits cell growth without vacuole formation. Sardomozide (3 μM) reduces intracellular SAMDC activity to 10%.
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In VitroSardomozide is a S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM in cell assay. Following treatment for 48 h with 3 μM Sardomozide, intracellular SAMDC activity is reduced to 10% of control. When the CHO/664 cells are grown in the presence of Sardomozide and during treatment with DENSPM, vacuole formation is not observed, and these cells are growth-inhibited and contain levels of DENSPM similar to the parental CHO cells.
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In Vivo——
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SynonymsCGP 48664 dihydrochloride
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PathwayOthers
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TargetOther Targets
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RecptorPlatelet aggregation
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Research Area——
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Indication——
Chemical Information
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CAS Number138794-73-7
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Formula Weight303.19
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Molecular FormulaC11H16Cl2N6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 10 mg/mL (32.98 mM)
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SMILESN=C(C1=CC=CC2=C1CCC2=NNC(N)=N)N.[H]Cl.[H]Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Chandler CM, et al. Improved extraction and complete mass spectral characterization of steroidal alkaloids from Veratrum californicum. Nat Prod Commun. 2013 Aug;8(8):1059-64.
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