SUVN-G3031

CAS No. 1394808-82-2

SUVN-G3031 ( SUVN-G 3031 )

Catalog No. M11647 CAS No. 1394808-82-2

SUVN-G3031 (SUVN-G 3031) is a potent, selective, orally active histamine H3 receptor (H3R) inverse agonist with Ki of 8.73 nM (hH3R).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 152 Get Quote
5MG 260 Get Quote
10MG 417 Get Quote
25MG 687 Get Quote
50MG 963 Get Quote
100MG 1287 Get Quote
500MG 2601 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    SUVN-G3031
  • Note
    Research use only, not for human use.
  • Brief Description
    SUVN-G3031 (SUVN-G 3031) is a potent, selective, orally active histamine H3 receptor (H3R) inverse agonist with Ki of 8.73 nM (hH3R).
  • Description
    SUVN-G3031 (SUVN-G 3031) is a potent, selective, orally active histamine H3 receptor (H3R) inverse agonist with Ki of 8.73 nM (hH3R); exhibited an IC50 of 20 nM with progressive inhibition of (R)-α-methylhistamine (0.03 μM) induced agonist activity in [35S]-GTPγS binding assay using CHO-K1 cells expressing human H3R membranes; reverses (R)-α-methylhistamine induced dipsogenia in vivo.Parkinson Disease Phase 1 Clinical
  • Synonyms
    SUVN-G 3031
  • Pathway
    GPCR/G Protein
  • Target
    Histamine Receptor
  • Recptor
    Histamine Receptor
  • Research Area
    Neurological Disease
  • Indication
    Parkinson Disease

Chemical Information

  • CAS Number
    1394808-82-2
  • Formula Weight
    373.50
  • Molecular Formula
    C21H31N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C1CC(C1)N2CCC(CC2)OC3=CC=C(C=C3)NC(=O)CN4CCOCC4
  • Chemical Name
    N-[4-(l-Cyclobutylpiperidin-4-yloxy) phenyl]-2-(morpholin-4-yl) acetamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Nirogi R, et al. J Med Chem. 2019 Jan 10. doi: 10.1021/acs.jmedchem.8b01280.
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