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SU-909
CAS No. 2126749-48-0
SU-909( SU909 | SU 909 | IKKα-IN-48 )
Catalog No. M13383 CAS No. 2126749-48-0
SU-909 (SU909, IKKα-IN-48) is a potent, selective IKKα inhibitor with Ki of 0.08±0.07 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameSU-909
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NoteResearch use only, not for human use.
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Brief DescriptionSU-909 (SU909, IKKα-IN-48) is a potent, selective IKKα inhibitor with Ki of 0.08±0.07 uM.
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DescriptionSU-909 (SU909, IKKα-IN-48) is a potent, selective IKKα inhibitor with Ki of 0.08±0.07 uM, 10-20-fold selectivity over IKKβ (IC50=1.0±0.28 uM); inhibits FCS-stimulated phosphorylation of p100 in U2OS cells with IC50 of 8.8 uM, inhibits the noncanonical NF-kB pathway without affecting IKKβ-dependent IKappa-Bα loss in the canonical pathway.
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In Vitro——
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In Vivo——
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SynonymsSU909 | SU 909 | IKKα-IN-48
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PathwayImmunology/Inflammation
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TargetIκB kinase (IKK)
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RecptorIκB kinase (IKK)
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Research Area——
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Indication——
Chemical Information
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CAS Number2126749-48-0
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Formula Weight314.323
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Molecular FormulaC13H10N6O2S
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name4-(2-Amino-5-cyano-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzenesulfonamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Anthony NG, et al. J Med Chem. 2017 Aug 24;60(16):7043-7066.
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