Cart
sales@molnova.com
SS-208
CAS No. 2245942-72-5
SS-208( SS208 )
Catalog No. M26826 CAS No. 2245942-72-5
SS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 215 | Get Quote |
|
| 10MG | 357 | Get Quote |
|
| 25MG | 597 | Get Quote |
|
| 50MG | 851 | Get Quote |
|
| 100MG | 1152 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameSS-208
-
NoteResearch use only, not for human use.
-
Brief DescriptionSS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.
-
DescriptionSS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.(In Vivo):In C57BL/6 mice injected immunogenic murine SM1 melanoma cells, SS-208 (25 mg/kg; i.p.) causes a significant reduction of the tumor growth.
-
In Vitro——
-
In VivoSS-208 (25 mg/kg, ip) significantly reduces the tumor growth in melanoma murine model. Animal Model:C57BL/6 mice injected immunogenic murine SM1 melanoma cells subcutaneously.Dosage:25 mg/kg.Administration:IP on day 4, 7, 12, 15 and 18.Result:Significantly reduced the tumor growth.
-
SynonymsSS208
-
PathwayCell Cycle/DNA Damage
-
TargetHDAC
-
Recptor5-HT2
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2245942-72-5
-
Formula Weight344.15
-
Molecular FormulaC13H11Cl2N3O4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 125 mg/mL (363.21 mM)
-
SMILESONC(=O)c1cc(CCNC(=O)c2ccc(Cl)c(Cl)c2)on1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Gonyou HW, et al. Effects of amperozide and azaperone on aggression and productivity of growing-finishing pigs. J Anim Sci. 1988 Nov;66(11):2856-64.
molnova catalog
related products
-
Detomidine HCl
Detomidine HCl produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors.
-
CHR-3996
CHR-3996 (Nanatinostat, VRx-3996, CHR3996, Tractinostat) is a potent, class I-selective, orally active HDAC inhibitor with IC50 of 3-7 nM for HDAC1/2/3.
-
JAK/HDAC-IN-1
JAK/HDAC-IN-1 is an effective JAK2/HDAC dual inhibitor (IC50s: 4 and 2 nM for JAK2 and HDAC). It also shows antiproliferative and proapoptotic activities in several hematological cell lines.
