SS-208

Research use only, not for human use.

SS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.

SS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.(In Vivo):In C57BL/6 mice injected immunogenic murine SM1 melanoma cells, SS-208 (25 mg/kg; i.p.) causes a significant reduction of the tumor growth.

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SS-208 (25 mg/kg, ip) significantly reduces the tumor growth in melanoma murine model. Animal Model:C57BL/6 mice injected immunogenic murine SM1 melanoma cells subcutaneously.Dosage:25 mg/kg.Administration:IP on day 4, 7, 12, 15 and 18.Result:Significantly reduced the tumor growth.

SS208

Cell Cycle/DNA Damage

HDAC

5-HT2

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2245942-72-5

344.15

C13H11Cl2N3O4

>98% (HPLC)

In Vitro:?DMSO : 125 mg/mL (363.21 mM)

ONC(=O)c1cc(CCNC(=O)c2ccc(Cl)c(Cl)c2)on1

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(-20℃)

With Ice Pack

≥ 2 years