Cart
sales@molnova.com
Home - Products - Cell Cycle/DNA Damage - PARP - SRI-011381

SRI-011381

CAS No. 1629138-41-5

SRI-011381( SRI-011381 | SRI 011381 | SRI011381 )

Catalog No. M17348 CAS No. 1629138-41-5

SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 36 In Stock
5MG 58 In Stock
10MG 102 In Stock
25MG 215 In Stock
50MG 357 In Stock
100MG 590 In Stock
200MG 826 In Stock
500MG 1224 In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    SRI-011381
  • Note
    Research use only, not for human use.
  • Brief Description
    SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
  • Description
    SRI-011381 is an agonist of the TGF-beta signaling pathway for treatment of Alzheimer's disease.
  • In Vitro
    ——
  • In Vivo
    Animal Model:YAPGFAP-CKO mice bearing experimental autoimmune encephalomyelitis (EAE)Dosage:30 mg/kg .Administration:Intraperitoneally injection; every 2 d; for 22 days Result:Significantly inhibited inflammatory infiltration and relieved the loss of neurons in YAPGFAP-CKO EAE mice.
  • Synonyms
    SRI-011381 | SRI 011381 | SRI011381
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    PARP
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1629138-41-5
  • Formula Weight
    329.48
  • Molecular Formula
    C20H31N3O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (151.75 mM)
  • SMILES
    O=C(NC1=NC2=CC=C(CN3CCC(C(C)(O)C)CC3)C=C2N1[C@H]4CC[C@@H](C(NC(C)C)=O)CC4)C5=CC=C(F)C=C5
  • Chemical Name
    N'-Cyclohexyl-N-(phenylmethyl)-N-(4-piperidinylmethyl)-urea

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • PARP-1-IN-4

    PARP-1-IN-4 is a potent PARP-1 inhibitor with potential anti-tumor activity, where inhibition of PARP-1 may be applied in cancer treatment.

  • Veliparib dihydrochl...

    Veliparib (ABT-888) is a potent, BBB penetrant, and orally active PARP inhibitor with IC50 of 5.2 and 2.9 nM for PARP-1 and PARP-2, respectively.

  • Desmethyl-VS-5584

    Desmethyl-VS-5584 is a dimethyl analog of VS-5584, which is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.

Sign In Join Free