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SRI-011381

CAS No. 1629138-41-5

SRI-011381( SRI-011381 | SRI 011381 | SRI011381 )

Catalog No. M17348 CAS No. 1629138-41-5

SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 36 In Stock
5MG 58 In Stock
10MG 102 In Stock
25MG 215 In Stock
50MG 357 In Stock
100MG 590 In Stock
200MG 826 In Stock
500MG 1224 In Stock
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Biological Information

  • Product Name
    SRI-011381
  • Note
    Research use only, not for human use.
  • Brief Description
    SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
  • Description
    SRI-011381 is an agonist of the TGF-beta signaling pathway for treatment of Alzheimer's disease.
  • In Vitro
    ——
  • In Vivo
    Animal Model:YAPGFAP-CKO mice bearing experimental autoimmune encephalomyelitis (EAE)Dosage:30 mg/kg .Administration:Intraperitoneally injection; every 2 d; for 22 days Result:Significantly inhibited inflammatory infiltration and relieved the loss of neurons in YAPGFAP-CKO EAE mice.
  • Synonyms
    SRI-011381 | SRI 011381 | SRI011381
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    PARP
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1629138-41-5
  • Formula Weight
    329.48
  • Molecular Formula
    C20H31N3O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (151.75 mM)
  • SMILES
    O=C(NC1=NC2=CC=C(CN3CCC(C(C)(O)C)CC3)C=C2N1[C@H]4CC[C@@H](C(NC(C)C)=O)CC4)C5=CC=C(F)C=C5
  • Chemical Name
    N'-Cyclohexyl-N-(phenylmethyl)-N-(4-piperidinylmethyl)-urea

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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