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Home - Products - Cell Cycle/DNA Damage - PARP - SRI-011381

SRI-011381

CAS No. 1629138-41-5

SRI-011381( SRI-011381 | SRI 011381 | SRI011381 )

Catalog No. M17348 CAS No. 1629138-41-5

SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 36 In Stock
5MG 58 In Stock
10MG 102 In Stock
25MG 215 In Stock
50MG 357 In Stock
100MG 590 In Stock
200MG 826 In Stock
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Biological Information

  • Product Name
    SRI-011381
  • Note
    Research use only, not for human use.
  • Brief Description
    SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
  • Description
    SRI-011381 is an agonist of the TGF-beta signaling pathway for treatment of Alzheimer's disease.
  • In Vitro
    ——
  • In Vivo
    Animal Model:YAPGFAP-CKO mice bearing experimental autoimmune encephalomyelitis (EAE)Dosage:30 mg/kg .Administration:Intraperitoneally injection; every 2 d; for 22 days Result:Significantly inhibited inflammatory infiltration and relieved the loss of neurons in YAPGFAP-CKO EAE mice.
  • Synonyms
    SRI-011381 | SRI 011381 | SRI011381
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    PARP
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1629138-41-5
  • Formula Weight
    329.48
  • Molecular Formula
    C20H31N3O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (151.75 mM)
  • SMILES
    O=C(NC1=NC2=CC=C(CN3CCC(C(C)(O)C)CC3)C=C2N1[C@H]4CC[C@@H](C(NC(C)C)=O)CC4)C5=CC=C(F)C=C5
  • Chemical Name
    N'-Cyclohexyl-N-(phenylmethyl)-N-(4-piperidinylmethyl)-urea

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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