SR11237

Research use only, not for human use.

SR11237 is a Pan retinoid X receptor (RXR) agonist. SR11237 causes RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element.

SR11237 is a Pan retinoid X receptor (RXR) agonist. SR11237 causes RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element.(In Vitro):SR11237 is effective at transactivating a chloramphenicol acetyltransferase reporter gene through RXRs but not retinoic acid receptors in COS-1 cells.(In Vivo):In Sprague-Dawley rats, SR11237 (BMS-649) (25 mg/kg; i.p.) Caused disturbed ossification and bone morphology in rats, including premature growth plate closure and infiltration of ossified tissue through the central epiphysis.

BMS-649

Others

Other Targets

Aurora A

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146670-40-8

380.5

C24H28O4

>98% (HPLC)

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CC1(C)CCC(C)(C)c2cc(ccc12)C1(OCCO1)c1ccc(cc1)C(O)=O

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(-20℃)

With Ice Pack

≥ 2 years