23-Butanedione

CAS No. 431-03-8

23-Butanedione( Biacetyl | Diacetyl )

Catalog No. M19605 CAS No. 431-03-8

23-Butanedione (Diacetyl) the molecule implicated in the disease known as popcorn lung has now been implicated in amyloid-β peptide toxicity associated with Alzheimer’s disease. Diacetyl accelerates amyloid-β aggregation-a hallmark of Alzheimer’s disease.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    23-Butanedione
  • Note
    Research use only, not for human use.
  • Brief Description
    23-Butanedione (Diacetyl) the molecule implicated in the disease known as popcorn lung has now been implicated in amyloid-β peptide toxicity associated with Alzheimer’s disease. Diacetyl accelerates amyloid-β aggregation-a hallmark of Alzheimer’s disease.
  • Description
    23-Butanedione (Diacetyl) the molecule implicated in the disease known as popcorn lung has now been implicated in amyloid-β peptide toxicity associated with Alzheimer’s disease. Diacetyl accelerates amyloid-β aggregation-a hallmark of Alzheimer’s disease. These preliminary findings raise the possibility of long-term neurological toxicity mediated by DA.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Biacetyl | Diacetyl
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    431-03-8
  • Formula Weight
    86.09
  • Molecular Formula
    C4H6O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    CC(=O)C(C)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Heinitz K et al. Toxicity mediated by soluble oligomers of beta-amyloid(1-42) on cholinergic SN56.B5.G4 cells. J Neurochem. 2006 Sep;98(6):1930-45.
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