SMS1-IN-1

CAS No. 1807943-38-9

SMS1-IN-1 ( —— )

Catalog No. M26452 CAS No. 1807943-38-9

SMS1-IN-1 is a potent inhibitor of sphingomyelin synthase 1 (SMS1, IC50 = 2.1 μM), and can be used in the atherosclerosis studies.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 147 Get Quote
10MG 237 Get Quote
25MG 483 Get Quote
50MG 698 Get Quote
100MG 972 Get Quote
500MG 1953 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    SMS1-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    SMS1-IN-1 is a potent inhibitor of sphingomyelin synthase 1 (SMS1, IC50 = 2.1 μM), and can be used in the atherosclerosis studies.
  • Description
    SMS1-IN-1 is a potent inhibitor of sphingomyelin synthase 1 (SMS1, IC50 = 2.1 μM), and can be used in the atherosclerosis studies. (In Vitro):SMS1-IN-1 (2.5, 10 and 50?μM) shows inhibitory effect against SMS1 in a dose-dependent manner.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    D2 receptor; D3 receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1807943-38-9
  • Formula Weight
    503.4
  • Molecular Formula
    C23H23BrN2O4S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Brc1ccc(CNC(=O)COc2ccc(cc2)S(=O)(=O)NCCc2ccccc2)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Holmes et al (2010) The identification of a selective DA D2 partial agonist, D3 antagonist displaying high levels of brain exposure. Bioorg.Med.Chem.Lett. 20 2013
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