SMIP004 ( —— )

Catalog No. M26820 CAS No. 143360-00-3

SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	106	Get Quote
5MG	165	Get Quote
10MG	250	Get Quote
25MG	417	Get Quote
50MG	600	Get Quote
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Biological Information

Product Name

SMIP004
Note

Research use only, not for human use.
Brief Description

SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells.
Description

SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells. (In Vitro):SMIP004 reduces the levels of positive cell cycle regulators upregulates cyclin-dependent kinase inhibitors. It also causes G1 arrest, inhibition of colony formation in soft agar, and cell death .(In Vivo):In SCID mice, SMIP004 effectively inhibits the growth of prostate and breast cancer xenografts .
Synonyms

——
Pathway

Apoptosis
Target

Apoptosis
Recptor

——
Research Area

——
Indication

——

Chemical Information

CAS Number

143360-00-3
Formula Weight

205.3
Molecular Formula

C13H19NO
Purity

>98% (HPLC)
Solubility

——
SMILES

CCCCc1ccc(NC(C)=O)c(C)c1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Xiang J, et al. Synthesis and evaluation of a paclitaxel-binding polymeric micelle for efficient breast cancer therapy. Sci China Life Sci. 2018 Apr;61(4):436-447.

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