SMIP004

CAS No. 143360-00-3

SMIP004 ( —— )

Catalog No. M26820 CAS No. 143360-00-3

SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 106 Get Quote
5MG 165 Get Quote
10MG 250 Get Quote
25MG 417 Get Quote
50MG 600 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
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Biological Information

  • Product Name
    SMIP004
  • Note
    Research use only, not for human use.
  • Brief Description
    SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells.
  • Description
    SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells. (In Vitro):SMIP004 reduces the levels of positive cell cycle regulators upregulates cyclin-dependent kinase inhibitors. It also causes G1 arrest, inhibition of colony formation in soft agar, and cell death .(In Vivo):In SCID mice, SMIP004 effectively inhibits the growth of prostate and breast cancer xenografts .
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    143360-00-3
  • Formula Weight
    205.3
  • Molecular Formula
    C13H19NO
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CCCCc1ccc(NC(C)=O)c(C)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Xiang J, et al. Synthesis and evaluation of a paclitaxel-binding polymeric micelle for efficient breast cancer therapy. Sci China Life Sci. 2018 Apr;61(4):436-447.
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