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SJ995973

CAS No. 2882065-25-8

SJ995973( —— )

Catalog No. M37131 CAS No. 2882065-25-8

SJ995973 is a highly potent bromodomain and extraterminal (BET) protein degrader and a BET PROTAC with potential anticancer activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 347 In Stock
5MG 655 In Stock
10MG 1121 In Stock
25MG 1638 In Stock
50MG 2190 In Stock
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Biological Information

  • Product Name
    SJ995973
  • Note
    Research use only, not for human use.
  • Brief Description
    SJ995973 is a highly potent bromodomain and extraterminal (BET) protein degrader and a BET PROTAC with potential anticancer activity.
  • Description
    SJ995973 (PROTAC) is a uniquely potent degrader ofbromodomain and extra-terminal (BET) proteins.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PROTACs
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2882065-25-8
  • Formula Weight
    730.28
  • Molecular Formula
    C37H40ClN7O5S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (136.93 mM; Ultrasonic )
  • SMILES
    CC=1C2=C(N3C([C@H](CC(NCCCCCNC(COC4=CC=C(C=C4)C5C(=O)NC(=O)CC5)=O)=O)N=C2C6=CC=C(Cl)C=C6)=NN=C3C)SC1C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Min J, et al. Phenyl-Glutarimides: Alternative Cereblon Binders for the Design of PROTACs. Angew Chem Int Ed Engl. 2021 Dec 13;60(51):26663-26670. ?
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