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SHR3824
CAS No. 1358579-22-2
SHR3824( SHR 3824 | SHR-3824 )
Catalog No. M11472 CAS No. 1358579-22-2
SHR3824 is a potent, selective SGLT2 inhibitor with IC50 of 2.38 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameSHR3824
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NoteResearch use only, not for human use.
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Brief DescriptionSHR3824 is a potent, selective SGLT2 inhibitor with IC50 of 2.38 nM.
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DescriptionSHR3824 is a potent, selective SGLT2 inhibitor with IC50 of 2.38 nM, >1000-fold selectivity over SGLT1; exhibits antidiabetic efficacy in several rodent models.Diabetes Phase 1 Clinical.
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In Vitro——
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In Vivo——
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SynonymsSHR 3824 | SHR-3824
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PathwayGPCR/G Protein
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TargetSGLT
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RecptorSGLT
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Research AreaMetabolic Disease
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IndicationDiabetes
Chemical Information
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CAS Number1358579-22-2
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Formula Weight454.875
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Molecular FormulaC22H24ClFO7
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(1R,2S,3S,4R,5R)-5-(4-Chloro-3-(4-ethoxy-3-fluorobenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Yan PK, et al. Acta Pharmacol Sin. 2014 May;35(5):613-24. doi: 10.1038/aps.2013.196.
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