SEW06622( —— )

Catalog No. M37325 CAS No. 261349-28-4

SEW06622 is a potent inhibitor of acetylcholinesterase (AChE) and beta-secretase-1 (BACE-1) and is a potential candidate for the treatment of Alzheimer's disease.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Size	Price / USD	Stock	Quantity
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5MG	459	Get Quote
10MG	657	Get Quote
25MG	994	Get Quote
50MG	1371	Get Quote
100MG	1773	Get Quote
500MG	Get Quote	Get Quote
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Biological Information

Product Name

SEW06622
Note

Research use only, not for human use.
Brief Description

SEW06622 is a potent inhibitor of acetylcholinesterase (AChE) and beta-secretase-1 (BACE-1) and is a potential candidate for the treatment of Alzheimer's disease.
Description

SEW06622 is a BACE-1 inhibitor with an IC50 value of 6.3 μM and can be used in Alzheimer's disease research.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

AChE
Recptor

AChE | BACE
Research Area

——
Indication

——

Chemical Information

CAS Number

261349-28-4
Formula Weight

338.44
Molecular Formula

C21H26N2O2
Purity

>98% (HPLC)
Solubility

——
SMILES

N(=CC=1C=CC=C(OC)C1OC)C2CCN(CC=3C=CC=CC3)CC2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Sharma P, et al. Design and development of multitarget-directed N-Benzylpiperidine analogs as potential candidates for the treatment of Alzheimer's disease. Eur J Med Chem. 2019 Apr 1;167:510-524.?

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