SEW06622

CAS No. 261349-28-4

SEW06622( —— )

Catalog No. M37325 CAS No. 261349-28-4

SEW06622 is a potent inhibitor of acetylcholinesterase (AChE) and beta-secretase-1 (BACE-1) and is a potential candidate for the treatment of Alzheimer's disease.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 459 In Stock
10MG 657 In Stock
25MG 1026 In Stock
50MG 1386 In Stock
100MG 1832 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    SEW06622
  • Note
    Research use only, not for human use.
  • Brief Description
    SEW06622 is a potent inhibitor of acetylcholinesterase (AChE) and beta-secretase-1 (BACE-1) and is a potential candidate for the treatment of Alzheimer's disease.
  • Description
    SEW06622 is a BACE-1 inhibitor with an IC50 value of 6.3 μM and can be used in Alzheimer's disease research.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    AChE
  • Recptor
    AChE | BACE
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    261349-28-4
  • Formula Weight
    338.44
  • Molecular Formula
    C21H26N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N(=CC=1C=CC=C(OC)C1OC)C2CCN(CC=3C=CC=CC3)CC2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Sharma P, et al. Design and development of multitarget-directed N-Benzylpiperidine analogs as potential candidates for the treatment of Alzheimer's disease. Eur J Med Chem. 2019 Apr 1;167:510-524.?
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