
SETDB1-TTD-IN-1
CAS No. 2755823-12-0
SETDB1-TTD-IN-1( —— )
Catalog No. M28873 CAS No. 2755823-12-0
SETDB1-TTD-IN-1 is a potent, selective and endogenous binder competitive inhibitor of SETDB1-TTD with a Kd of 88 nM.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 599 | Get Quote |
![]() ![]() |
10MG | 853 | Get Quote |
![]() ![]() |
25MG | 1278 | Get Quote |
![]() ![]() |
50MG | 1701 | Get Quote |
![]() ![]() |
100MG | 2313 | Get Quote |
![]() ![]() |
200MG | Get Quote | Get Quote |
![]() ![]() |
500MG | Get Quote | Get Quote |
![]() ![]() |
1G | Get Quote | Get Quote |
![]() ![]() |
Biological Information
-
Product NameSETDB1-TTD-IN-1
-
NoteResearch use only, not for human use.
-
Brief DescriptionSETDB1-TTD-IN-1 is a potent, selective and endogenous binder competitive inhibitor of SETDB1-TTD with a Kd of 88 nM.
-
DescriptionSETDB1-TTD-IN-1 is a potent, selective and endogenous binder competitive inhibitor of SETDB1-TTD with a Kd of 88 nM.(In Vitro):SETDB1-TTD-IN-1 (2.5-40 μM) efficiently and dose-dependently stabilizes the SETDB1-TTD protein in HEK293T cells. SETDB1-TTD-IN-1 (2.5-40 μM; 24 h) significantly affected the expression of 72 genes in human acute monocytic leukemia THP-1 cells. SETDB1-TTD-IN-1 shows some activity for 53BP1 and JMJD2A, with Kds of 4.3 μM and 86 μM, respectively. SETDB1-TTD-IN-1 does not show activity against 14 of the 16 tested tudor domains (Kd>100 μM).
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayChromatin/Epigenetic
-
TargetHistone Demethylase
-
RecptorFusion protein|RSV
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2755823-12-0
-
Formula Weight469.58
-
Molecular FormulaC28H31N5O2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 125 mg/mL (266.20 mM)
-
SMILESCN1C[C@H](C[C@H](C1)NC2=NC3=C(NC=C3)C(N2CC=C)=O)C4=CC=C(C=C4)OCC5=CC=CC=C5
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Roymans D, et al. Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor. Nat Commun. 2017 Aug 1;8(1):167.
molnova catalog



related products
-
Zavondemstat
Zavondemstat (QC8222 free base) is a histone lysine demethylase 4 (KDM4) inhibitor with anticancer and antitumor activity for the study of triple-negative and breast cancers.
-
ORY-1001 trans and c...
ORY-1001 (RG-6016) is a highly potent, selective inhibitor of lysine-specific demethylase KDM1A (LSD1) with IC50 of 18 nM.
-
MS049 2HCl
MS049 is a potent and selective inhibitor of PRMT4 (IC50 = 34 nM) and PRMT6 (IC50 = 43 nM).