SDH-IN-2

CAS No. 1823354-06-8

SDH-IN-2( —— )

Catalog No. M36610 CAS No. 1823354-06-8

SDH-IN-2, a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 0.55 μg/mL, demonstrates antifungal activity against plant pathogenic fungi, with EC50 values ranging from 3.82 to 9.81 μg/mL.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 112 Get Quote
5MG 169 Get Quote
10MG 264 Get Quote
25MG 457 Get Quote
50MG 687 Get Quote
100MG 888 Get Quote
500MG 1782 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    SDH-IN-2
  • Note
    Research use only, not for human use.
  • Brief Description
    SDH-IN-2, a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 0.55 μg/mL, demonstrates antifungal activity against plant pathogenic fungi, with EC50 values ranging from 3.82 to 9.81 μg/mL.
  • Description
    SDH-IN-2 is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 0.55 μg/mL. SDH-IN-2 is also an antifungal agent. SDH-IN-2 inhibits phytopathogenic fungia with average EC50 values of 3.82-9.81 μg/mL for all the fungi. SDH-IN-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antifungal
  • Recptor
    Antifungal
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1823354-06-8
  • Formula Weight
    213.16
  • Molecular Formula
    C10H6F3NO
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (1172.83 mM; Ultrasonic )
  • SMILES
    C(F)(F)(F)C1=CC=C(NC(C#C)=O)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhang YH, et al. Discovery of N-Phenylpropiolamide as a Novel Succinate Dehydrogenase Inhibitor Scaffold with Broad-Spectrum Antifungal Activity on Phytopathogenic Fungi. J Agric Food Chem. 2023 Mar 1;71(8):3681-3693. ?
molnova catalog
related products
  • Lomeguatrib

    Lomeguatrib, a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) .

  • APX2039

    APX2039 is an orally active fungal Gwt1 enzyme inhibitor and a prodrug of the novel Gwt2096 inhibitor APX1.APX2039 exhibits potent anti-Kryptococcal activity against C. neoformans and C. gattii.

  • Cyclo(L-leucyl-L-val...

    Cyclo(L-leucyl-L-valyl) is a polymorphic compound isolated from the secondary metabolite of Streptomyces quinquefasciatus YIM, which has not yet shown antimicrobial activity.