SC-26196

CAS No. 218136-59-5

SC-26196 ( —— )

Catalog No. M21997 CAS No. 218136-59-5

SC-26196 is an orally active inhibitor of Delta6 desaturase (D6D) with IC50 of 0.2 μM in a rat liver microsomal assay, with antiinflammatory properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 56 In Stock
5MG 88 In Stock
10MG 133 In Stock
25MG 221 In Stock
50MG 327 In Stock
100MG 485 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    SC-26196
  • Note
    Research use only, not for human use.
  • Brief Description
    SC-26196 is an orally active inhibitor of Delta6 desaturase (D6D) with IC50 of 0.2 μM in a rat liver microsomal assay, with antiinflammatory properties.
  • Description
    SC-26196 is an orally active inhibitor of Delta6 desaturase (D6D) with IC50 of 0.2 μM in a rat liver microsomal assay, with antiinflammatory properties. The FADS2 inhibitor SC26196 reduced PBMC, but not Jurkat cell, proliferation suggesting PUFA synthesis is involved in regulating mitosis in PBMCs.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    D6D
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    218136-59-5
  • Formula Weight
    423.55
  • Molecular Formula
    C27H29N5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:4mg/ml (9.44 Mm; Need ultrasonic)
  • SMILES
    C1CN(CCN1CCCC(C#N)(C2=CC=CC=C2)C3=CC=CC=C3)N=CC4=CN=CC=C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Obukowicz MG, et al. Novel, selective delta6 or delta5 fatty acid desaturase inhibitors as antiinflammatory agents in mice. J Pharmacol Exp Ther. 1998 Oct;287(1):157-66.
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