SC-202671
CAS No. 312917-14-9
SC-202671 ( TCS JNK 5a, TCS-JNK-5a, JNK Inhibitor IX, SC-202671 )
Catalog No. M18411 CAS No. 312917-14-9
TCS JNK 5a is an effective, specific inhibitor of JNK3(pIC50= 6.7), JNK2(pIC50=6.5).
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 35 | In Stock |
|
10MG | 58 | In Stock |
|
25MG | 104 | In Stock |
|
50MG | 177 | In Stock |
|
100MG | 267 | In Stock |
|
500MG | 655 | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
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Product NameSC-202671
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NoteResearch use only, not for human use.
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Brief DescriptionTCS JNK 5a is an effective, specific inhibitor of JNK3(pIC50= 6.7), JNK2(pIC50=6.5).
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DescriptionTCS JNK 5a, also called JNK Inhibitor IX , is a selective and potent inhibitor of JNK inhibitor. Exposure of human Jurkat T cells to SC-202671 targeting JNK2 and JNK3, caused apoptotic DNA fragmentation along with G2/M arrest, phosphorylation of Bcl-2, Mcl-1, and Bim, Δψm loss, and activation of Bak and caspase cascade.
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SynonymsTCS JNK 5a, TCS-JNK-5a, JNK Inhibitor IX, SC-202671
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PathwayOthers
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TargetOther Targets
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RecptorJNK2; JNK3
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number312917-14-9
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Formula Weight332.42
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Molecular FormulaC20H16N2OS
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Purity98%
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SolubilityDMSO : ≥ 51 mg/mL; 153.42 mM
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SMILESC1CCc2c(C1)c(c(s2)NC(=O)c1cccc2ccccc12)C#N
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Chemical NameN-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-1-naphthamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Angell RM, et al. Bioorg Med Chem Lett. 2007, 17(5), 1296-1301.2. Rudolf E, et al. Toxicol Lett. 2009, 188(3), 236-242.
molnova catalog
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