Cart
sales@molnova.com
44'-DIMETHOXYBENZIL
CAS No. 1226-42-2
44'-DIMETHOXYBENZIL( p-Anisil )
Catalog No. M20521 CAS No. 1226-42-2
44'-Dimethoxybenzil is a human intestinal carboxyl esterase (hiCE) inhibitor( Ki : 70 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | 27 | In Stock |
|
Biological Information
-
Product Name44'-DIMETHOXYBENZIL
-
NoteResearch use only, not for human use.
-
Brief Description44'-Dimethoxybenzil is a human intestinal carboxyl esterase (hiCE) inhibitor( Ki : 70 nM).
-
Description44'-Dimethoxybenzil is a human intestinal carboxyl esterase (hiCE) inhibitor( Ki : 70 nM).
-
In VitroBy reducing irinotecaninduced diarrhea, hiCE inhibitors (e.g., 4,4'-Dimethoxybenzil, Compound 8) can improve the anti-cancer efficacy of irinotecan. To find effective hiCE inhibitors, a new virtual screening protocol that combines pharmacophore models derived from the hiCE structure and its ligands has been proposed.
-
In Vivo——
-
Synonymsp-Anisil
-
PathwayOthers
-
TargetOther Targets
-
RecptorhiCE
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1226-42-2
-
Formula Weight270.28
-
Molecular FormulaC16H14O4
-
Purity>98% (HPLC)
-
SolubilityDMSO:50 mg/mL (184.99 mM)
-
SMILESCOc1ccc(cc1)C(=O)C(=O)c1ccc(OC)cc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Guodong Z Hu G E Qiong G U et al. Predicting hiCE inhibitors based upon pharmacophore models derived from the receptor and its ligands[J]. Science China(Chemistry) 2013(10):80-90.
molnova catalog
related products
-
Epicatechin 3-O-(4-O...
Epicatechin 3-O-(4-O-methylgallate)
-
Byakangelicin
Byakangelicin is an antineoplastic agent.
-
Amyloid β-Protein (1...
Amyloid β-Protein (1-12) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development.
