SBHA

CAS No. 38937-66-5

SBHA ( Suberohydroxamic acid; Suberoyl bis-hydroxamic acid )

Catalog No. M24349 CAS No. 38937-66-5

SBHA (suberohydroxamic acid) is a Histone deacetylase (HDAC) inhibitor. HDAC is required for transcriptional modulation, cell cycle regulation and development.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG 27 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    SBHA
  • Note
    Research use only, not for human use.
  • Brief Description
    SBHA (suberohydroxamic acid) is a Histone deacetylase (HDAC) inhibitor. HDAC is required for transcriptional modulation, cell cycle regulation and development.
  • Description
    SBHA (suberohydroxamic acid) is a Histone deacetylase (HDAC) inhibitor. HDAC is required for transcriptional modulation, cell cycle regulation and development. It is an enzyme that deacetylates lysine residues on the N-terminal of the core histones.
  • Synonyms
    Suberohydroxamic acid; Suberoyl bis-hydroxamic acid
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC1; HDAC3
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    38937-66-5
  • Formula Weight
    204.2
  • Molecular Formula
    C8H16N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 49 mg/mL (239.93 mM; Need ultrasonic); H2O : 8.16 mg/mL (40 mM; Need ultrasonic)
  • SMILES
    ONC(CCCCCCC(NO)=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Richon VM, Emiliani S, Verdin E et al. A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases. Proc Natl Acad Sci U S A. 1998 Mar 17; 95(6):3003-7.
molnova catalog
related products
  • MPT0E028

    MPT0E028 (MPT 0E028) is a potent HDAC inhibitor that inhibits nuclear HDAC activity with IC50 of 11.1 nM in HeLa cells.

  • Exifone

    Exifone is a mixed, nonessential activator of HDAC1 that is capable of binding to both free and substrate-bound enzyme, resulting in an increased relative maximal rate of HDAC1-catalyzed deacetylation.

  • ACY-1083

    ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor (IC50: 3 nM). It is 260-fold more selective for HDAC6 than all other classes of HDAC isoforms.