SBHA

CAS No. 38937-66-5

SBHA ( Suberohydroxamic acid; Suberoyl bis-hydroxamic acid )

Catalog No. M24349 CAS No. 38937-66-5

SBHA (suberohydroxamic acid) is a Histone deacetylase (HDAC) inhibitor. HDAC is required for transcriptional modulation, cell cycle regulation and development.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    SBHA
  • Note
    Research use only, not for human use.
  • Brief Description
    SBHA (suberohydroxamic acid) is a Histone deacetylase (HDAC) inhibitor. HDAC is required for transcriptional modulation, cell cycle regulation and development.
  • Description
    SBHA (suberohydroxamic acid) is a Histone deacetylase (HDAC) inhibitor. HDAC is required for transcriptional modulation, cell cycle regulation and development. It is an enzyme that deacetylates lysine residues on the N-terminal of the core histones.
  • Synonyms
    Suberohydroxamic acid; Suberoyl bis-hydroxamic acid
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC1; HDAC3
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    38937-66-5
  • Formula Weight
    204.2
  • Molecular Formula
    C8H16N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 49 mg/mL (239.93 mM; Need ultrasonic); H2O : 8.16 mg/mL (40 mM; Need ultrasonic)
  • SMILES
    ONC(CCCCCCC(NO)=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Richon VM, Emiliani S, Verdin E et al. A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases. Proc Natl Acad Sci U S A. 1998 Mar 17; 95(6):3003-7.
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