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Home - Products - Cell Cycle/DNA Damage - HDAC - SB-379278A

SB-379278A

CAS No. 146366-04-3

SB-379278A( SB379278A | SB 379278A )

Catalog No. M11990 CAS No. 146366-04-3

A potent and selective HDAC8 inhibitor with IC50 of 0.5 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    SB-379278A
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent and selective HDAC8 inhibitor with IC50 of 0.5 uM.
  • Description
    A potent and selective HDAC8 inhibitor with IC50 of 0.5 uM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SB379278A | SB 379278A
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    146366-04-3
  • Formula Weight
    177.225
  • Molecular Formula
    C8H7N3S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C1=CN=CC=C1C2=CNC(=S)N2
  • Chemical Name
    4-Pyridin-4-yl-1,3-dihydroimidazole-2-thione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hu E, et al. J Pharmacol Exp Ther. 2003 Nov;307(2):720-8. 2. Chakrabarti A, et al. Future Med Chem. 2016 Sep;8(13):1609-34. 3. Heimburg T, et al. J Med Chem. 2017 Dec 15. doi: 10.1021/acs.jmedchem.7b01447.
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