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S3I-M2001
CAS No. 1003580-86-6
S3I-M2001( S3I M2001 | Bromohydroxyacetone phosphate )
Catalog No. M10032 CAS No. 1003580-86-6
S3I-M2001 (Bromohydroxyacetone phosphate) is an oxazole-based peptidomimetic of the STAT3 SH2 domain-binding phosphotyrosine peptide that selectively disrupts active STAT3:STAT3 dimers.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 372 | Get Quote |
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| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameS3I-M2001
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NoteResearch use only, not for human use.
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Brief DescriptionS3I-M2001 (Bromohydroxyacetone phosphate) is an oxazole-based peptidomimetic of the STAT3 SH2 domain-binding phosphotyrosine peptide that selectively disrupts active STAT3:STAT3 dimers.
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DescriptionS3I-M2001 (Bromohydroxyacetone phosphate) is an oxazole-based peptidomimetic of the STAT3 SH2 domain-binding phosphotyrosine peptide that selectively disrupts active STAT3:STAT3 dimers; inhibits Stat3-dependent transcriptional regulation of tumor survival genes, such as Bcl-xL; suppresses Stat3-dependent malignant transformation, survival, and migration and invasion of mouse and human cancer cells harboring persistently activated Stat3; inhibits growth of human breast tumor xenografts.
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In Vitro——
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In Vivo——
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SynonymsS3I M2001 | Bromohydroxyacetone phosphate
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PathwayJAK/STAT Signaling
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TargetSTAT
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RecptorSTAT
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Research Area——
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Indication——
Chemical Information
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CAS Number1003580-86-6
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Formula Weight508.511
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Molecular FormulaC27H29N2O6P
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Purity>98% (HPLC)
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Solubility——
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SMILESCCCCCCNC(=O)C1=C(OC(=N1)C2=CC=CC3=CC=CC=C32)CC4=CC=C(C=C4)OP(=O)(O)O
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Chemical Name4-{[4-(Hexylcarbamoyl)-2-(1-naphthyl)-1,3-oxazol-5-yl]methyl}phen yl dihydrogen phosphate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Siddiquee KA, et al. ACS Chem Biol. 2007 Dec 21;2(12):787-98.
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