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AS2863619
CAS No. 2241300-51-4
AS2863619 ( —— )
Catalog No. M21957 CAS No. 2241300-51-4
AS2863619 is an orally active?inhibitor of cyclin-dependent kinase 8 (CDK8) and CDK19 (IC50s of 0.61 nM and 4.28 nM, respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 170 | Get Quote |
|
| 5MG | 260 | Get Quote |
|
| 10MG | 410 | Get Quote |
|
| 25MG | 678 | Get Quote |
|
| 50MG | 954 | Get Quote |
|
| 100MG | 1287 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameAS2863619
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NoteResearch use only, not for human use.
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Brief DescriptionAS2863619 is an orally active?inhibitor of cyclin-dependent kinase 8 (CDK8) and CDK19 (IC50s of 0.61 nM and 4.28 nM, respectively).
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DescriptionAS2863619 is an orally active?inhibitor of cyclin-dependent kinase 8 (CDK8) and CDK19 (IC50s of 0.61 nM and 4.28 nM, respectively).
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Synonyms——
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PathwayJAK/STAT Signaling
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TargetSTAT
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RecptorSTAT5;CDK8;CDK19
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Research Area——
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Indication——
Chemical Information
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CAS Number2241300-51-4
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Formula Weight405.24
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Molecular FormulaC16H14Cl2N8O
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Purity>98% (HPLC)
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SolubilityDMSO:245 mg/ml(604.58 mM; Need ultrasonic)
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SMILESCl.Cl.Cc1nc2ccc(cc2[nH]1)-n1c(nc2cnccc12)-c1nonc1N
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Akamatsu M, et al. Conversion of antigen-specific effector/memory T cells into Foxp3-expressing Treg cells by inhibition of CDK8/19. Sci Immunol. 2019 Oct 25;4(40). pii: eaaw2707.
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