S-23

Research use only, not for human use.

S-23 is an oral selective androgen receptor modulator (SARM) with a Ki of 1.7 nM. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats.

S-23 is an oral selective androgen receptor modulator (SARM) with a Ki of 1.7 nM. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats.(In Vitro):Administration of 10 nM S-23 induces AR-mediated transcriptional activation in CV-1 cells .(In Vivo):Administration of S-23 to castrated animals increases the weights of the androgen-dependent organ dose-dependently with the ED50s of S-23 in the prostate and levator ani muscle of 0.43 and 0.079 mg/d, respectively.

S 23; S23; (S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide

Endocrinology/Hormones

Androgen Receptor (AR)

PDE3

——

——

1010396-29-8

416.8

C18H13ClF4N2O3

>98% (HPLC)

——

C[C@](O)(COc1ccc(Cl)c(F)c1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F

——

(-20℃)

With Ice Pack

≥ 2 years