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Resminostat
CAS No. 864814-88-0
Resminostat ( RAS2410;4SC-201;RAS 2410;RAS-2410 )
Catalog No. M16273 CAS No. 864814-88-0
A potent inhibitor of HDAC1/3/6 with IC50s of 43-72 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 88 | In Stock |
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| 10MG | 162 | In Stock |
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| 25MG | 289 | In Stock |
|
| 50MG | 519 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameResminostat
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NoteResearch use only, not for human use.
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Brief DescriptionA potent inhibitor of HDAC1/3/6 with IC50s of 43-72 nM.
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DescriptionA potent inhibitor of HDAC1/3/6 with IC50s of 43-72 nM; induces hyperacetylation of histone H4 and apoptosis in MM cell lines (IC50=2.5-3 uM); decreases levels of cyclin D1, cdc25a, Cdk4 and pRb as well as upregulation of p21; downregulates phosphorylation of 4E-BP1 and p70S6k.Liver Cancer Phase 2 Clinical
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SynonymsRAS2410;4SC-201;RAS 2410;RAS-2410
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHDAC1; HDAC3; HDAC6
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Research AreaCancer
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IndicationLiver Cancer
Chemical Information
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CAS Number864814-88-0
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Formula Weight349.40
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Molecular FormulaC16H19N3O4S
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C(NO)/C=C/C1=CN(S(=O)(C2=CC=C(CN(C)C)C=C2)=O)C=C1
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Chemical Name2-Propenamide, 3-[1-[[4-[(dimethylamino)methyl]phenyl]sulfonyl]-1H-pyrrol-3-yl]-N-hydroxy-, (2E)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Mandl-Weber S, et al. Br J Haematol. 2010 May;149(4):518-28.
2. Fu M, et al. Biochem Biophys Res Commun. 2016 Sep 2;477(4):527-33.
3. Enzenhofer E, et al. Head Neck. 2017 May;39(5):900-907.
2. Fu M, et al. Biochem Biophys Res Commun. 2016 Sep 2;477(4):527-33.
3. Enzenhofer E, et al. Head Neck. 2017 May;39(5):900-907.
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