Remimazolam

CAS No. 308242-62-8

Remimazolam ( CNS-7056,CNS 7056,CNS7056 )

Catalog No. M22876 CAS No. 308242-62-8

Remimazolam is a benzodiazepine derivative drug as an alternative to the short-acting imidazobenzodiazepine midazolam, for use in induction of anaesthesia and conscious sedation for minor invasive procedures.?Remimazolam was found to be both faster acting and shorter lasting than midazolam, and human clinical trials showed a faster recovery time and predictable, consistent pharmacokinetics, suggesting some advantages over existing drugs for these applications.?

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 357 In Stock
10MG 596 In Stock
25MG 882 In Stock
50MG Get Quote In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Remimazolam
  • Note
    Research use only, not for human use.
  • Brief Description
    Remimazolam is a benzodiazepine derivative drug as an alternative to the short-acting imidazobenzodiazepine midazolam, for use in induction of anaesthesia and conscious sedation for minor invasive procedures.?Remimazolam was found to be both faster acting and shorter lasting than midazolam, and human clinical trials showed a faster recovery time and predictable, consistent pharmacokinetics, suggesting some advantages over existing drugs for these applications.?
  • Description
    Remimazolam is a benzodiazepine derivative drug as an alternative to the short-acting imidazobenzodiazepine midazolam, for use in induction of anaesthesia and conscious sedation for minor invasive procedures.?Remimazolam was found to be both faster acting and shorter lasting than midazolam, and human clinical trials showed a faster recovery time and predictable, consistent pharmacokinetics, suggesting some advantages over existing drugs for these applications.?Mice showed significantly increased time to movement outside a set perimeter after 5-minute exposure to increasing concentrations (10-25 mg/mL solutions) of inhaled remimazolam aerosols.?Differences in mean (95% confidence interval) time to movement from pretest baseline group (0.05 [0.01-0.09] minutes) were 11 (4-18), 15 (5-26), 30 (19-41), and 109 (103-115) minutes after exposure to remimazolam aerosol of 10, 15, 20, and 25 mg/mL, respectively (P = .007 - P
  • Synonyms
    CNS-7056,CNS 7056,CNS7056
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    nervous system
  • Indication
    Anesthesia

Chemical Information

  • CAS Number
    308242-62-8
  • Formula Weight
    439.31
  • Molecular Formula
    C21H19BrN4O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:Soluble; Water:Insoluble
  • SMILES
    CC1=CN=C2N1C3=C(C=C(C=C3)Br)C(=NC2CCC(=O)OC)C4=CC=CC=N4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Rower, Joseph, Sakata, et al. Inhaled Remimazolam Potentiates Inhaled Remifentanil in Rodents[J]. Anesthesia and Analgesia: Journal of the International Anesthesia Research Society, 2017.
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