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Remibrutinib
CAS No. 1787294-07-8
Remibrutinib( —— )
Catalog No. M23801 CAS No. 1787294-07-8
Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 210 | In Stock |
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| 10MG | 340 | In Stock |
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| 25MG | 572 | In Stock |
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| 50MG | 797 | In Stock |
|
| 100MG | 1107 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRemibrutinib
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NoteResearch use only, not for human use.
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Brief DescriptionRemibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood.
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DescriptionRemibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood. Remibrutinib is an effective and orally active Bruton tyrosine kinase inhibitor (IC50: 1 nM). Remibrutinib has the potential for Chronic urticaria (CU) treatment.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayTyrosine Kinase
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TargetBTK
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RecptorBTK
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Research Area——
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Indication——
Chemical Information
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CAS Number1787294-07-8
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Formula Weight507.53
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Molecular FormulaC27H27F2N5O3
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Purity>98% (HPLC)
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SolubilityDMSO:125 mg/mL (246.29 mM; Need ultrasonic)
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SMILESCC1=C(C=C(C=C1NC(=O)C2=C(C=C(C=C2)C3CC3)F)F)C4=C(C(=NC=N4)N)OCCN(C)C(=O)C=C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Daniela Angst, et al. Novel amino pyrimidine derivatives. Patent WO2015079417A1.
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