Rafoxanide ( Rafoxanide; BRN 2228187; Disalan; Duofas; EINECS 245-148-9 )

Catalog No. M13618 CAS No. 22662-39-1

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Product Name

Rafoxanide
Note

Research use only, not for human use.
Brief Description

A salicylanilide anthelmintic agent that also shows to be an allosteric inhibitor of SPAK and OSR1.
Description

A salicylanilide anthelmintic agent that also shows to be an allosteric inhibitor of SPAK and OSR1; has antiangiogenic activity in zebrafish with IC50 of 1.69 uM on the intersegmental vessels and 1.45 uM on the subintestinal vessels.Parasite Infection Approved
Synonyms

Rafoxanide; BRN 2228187; Disalan; Duofas; EINECS 245-148-9
Pathway

Microbiology/Virology
Target

Parasite
Recptor

Parasite
Research Area

Infection
Indication

Parasite Infection

CAS Number

22662-39-1
Formula Weight

626.01
Molecular Formula

C19H11Cl2I2NO3
Purity

>98% (HPLC)
Solubility

DMSO: ≥ 31 mg/mL
SMILES

C1=CC(=CC=C1OC2=C(C=C(C=C2)NC(=O)C3=C(C(=CC(=C3)I)I)O)Cl)Cl
Chemical Name

Benzamide, N-[3-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3,5-diiodo-

1. AlAmri MA, et al. ChemMedChem. 2017 May 9;12(9):639-645.
2. Zhu XY, et al. Assay Drug Dev Technol. 2016 Apr 5.

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