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Radezolid

CAS No. 869884-78-6

Radezolid( RX-1741 )

Catalog No. M26804 CAS No. 869884-78-6

Radezolid is a novel oxazolidinone antibiotic agent.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Radezolid
  • Note
    Research use only, not for human use.
  • Brief Description
    Radezolid is a novel oxazolidinone antibiotic agent.
  • Description
    Radezolid is a novel oxazolidinone antibiotic agent.(In Vitro):Radezolid displays a greater potency than linezolid, independent of the bacteria tested, when concentrations are expressed on a weight (mg/L) basis. Radezolid shows an improved potency compared to that of linezolid when concentrations are expressed on a weight (mg/L) basis. Radezolid MICs are systematically equal to or lower (up to 3 log2 dilutions) than those of linezolid for all linezolid-susceptible strains, with an 8-fold difference for the linezolid-resistant strains. Radezolid and TR-700 perform well against 3-copy G2447T, G2576T, and G2576T/T2571C mutants .
  • In Vitro
    Radezolid MICs are systematically equal to or lower (up to 3 log2 dilutions) than those of linezolid for all linezolid-susceptible strains, with an 8-fold difference for the linezolid-resistant strains. Radezolid shows a greater potency than linezolid, independent of the bacteria tested, when concentrations are expressed on a weight (mg/L) basis. Radezolid shows an improved potency compared to that of linezolid when concentrations are expressed on a weight (mg/L) basis. Radezolid and TR-700 perform well against 3-copy G2447T, G2576T, and G2576T/T2571C mutants.
  • In Vivo
    ——
  • Synonyms
    RX-1741
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    TNIK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    869884-78-6
  • Formula Weight
    438.463
  • Molecular Formula
    C22H23FN6O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 25 mg/mL (57.02 mM)
  • SMILES
    CC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(c(F)c1)-c1ccc(CNCc2cnn[nH]2)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lee Y, et al. Synergistic inhibition effect of TNIK inhibitor KY-05009 and receptor tyrosine kinase inhibitor dovitinib on IL-6-induced proliferation and Wnt signaling pathway in human multiple myeloma cells. Oncotarget. 2017 Jun 20;8(25):41091-41101.
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