Picloxydine

Research use only, not for human use.

Picloxydine has antiplaque and antibacterial activity. Picloxydine has a destructive effect on the bacterial cell wall and plasma membrane, which leads to cell lysis and release of intracellular components.

Picloxydine has antiplaque and antibacterial activity. Picloxydine has a destructive effect on the bacterial cell wall and plasma membrane, which leads to cell lysis and release of intracellular components.(In Vivo):While picloxydine in higher concentration suppressed the oral flora more effectively than chlorhexidine, the latter agent inhibited plaque development to a much greater extent.?This lack of correlation between antibacterial and antiplaque activity can be related to structural differences between these two bis-biguanides.

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GPCR/G Protein

Antibacterial

Caspase-3; Caspase-9; ERK; MEK1

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5636-92-0

475.4

C20H24Cl2N10

>98% (HPLC)

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Clc1ccc(NC(=N)NC(=N)N2CCN(CC2)C(=N)NC(=N)Nc2ccc(Cl)cc2)cc1

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(-20℃)

With Ice Pack

≥ 2 years