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RH01386
CAS No. 301177-36-6
RH01386 ( —— )
Catalog No. M26579 CAS No. 301177-36-6
RH01386 is a small molecule that can prevent ER stress-induced β cell dysfunction and death, and inhibits proapoptotic gene expression,has the potential for type 2 diabetes treatment. RH01386 restores ER stress-impaired glucose-stimulated insulin secretion responses.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 273 | Get Quote |
|
| 10MG | 402 | Get Quote |
|
| 25MG | 664 | Get Quote |
|
| 50MG | 888 | Get Quote |
|
| 100MG | 1242 | Get Quote |
|
| 500MG | 2511 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameRH01386
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NoteResearch use only, not for human use.
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Brief DescriptionRH01386 is a small molecule that can prevent ER stress-induced β cell dysfunction and death, and inhibits proapoptotic gene expression,has the potential for type 2 diabetes treatment. RH01386 restores ER stress-impaired glucose-stimulated insulin secretion responses.
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DescriptionRH01386 is a small molecule that can prevent ER stress-induced β cell dysfunction and death, and inhibits proapoptotic gene expression,has the potential for type 2 diabetes treatment. RH01386 restores ER stress-impaired glucose-stimulated insulin secretion responses.(In Vitro):ATP levels in βTC6 cells treated with (tunicamycin) Tm increase by RH01386.RH01386 exhibits a EC50 value of 1.894 μM. RH01386 dose-dependently inhibits (tunicamycin) Tm-induced cell death, and inhibits the activity of caspase-3, a downstream effector of the apoptotic pathway in βTC6 cells.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number301177-36-6
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Formula Weight424.4
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Molecular FormulaC18H15F3N4O3S
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Purity>98% (HPLC)
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Solubility——
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SMILES[O-][N+](=O)c1cc(ccc1Sc1nc(C2CCCCC2)c(C#N)c(=O)[nH]1)C(F)(F)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Wang XX, et al. The implementation of high fermentative 2,3-butanediol production from xylose by simultaneous additions of yeast extract, Na2EDTA, and acetic acid. N Biotechnol. 2015 Aug 3.
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