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R-7050
CAS No. 303997-35-5
R-7050 ( R-7050; R 7050; R7050; TNF-α Antagonist III )
Catalog No. M18394 CAS No. 303997-35-5
R-7050 is a tumor necrosis factor receptor (TNFR) antagonist with greater selectivity toward TNFα.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 34 | In Stock |
|
| 5MG | 55 | In Stock |
|
| 10MG | 87 | In Stock |
|
| 25MG | 195 | In Stock |
|
| 50MG | 267 | In Stock |
|
| 100MG | 439 | In Stock |
|
| 500MG | 954 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameR-7050
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NoteResearch use only, not for human use.
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Brief DescriptionR-7050 is a tumor necrosis factor receptor (TNFR) antagonist with greater selectivity toward TNFα.
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DescriptionR-7050 is a TNF-α receptor antagonist. It acts by blocking receptor-adaptor molecule complex formation and subsequent receptor internalization, but not TNF-α ligand-receptor binding.
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SynonymsR-7050; R 7050; R7050; TNF-α Antagonist III
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PathwayOthers
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TargetOther Targets
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RecptorTNF-α
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number303997-35-5
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Formula Weight380.77
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Molecular FormulaC16H8ClF3N4S
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Purity98%
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SolubilityDMSO : 25 mg/mL 65.66 mM;
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SMILESFC(F)(F)c3nnc2c(nc1ccc(Cl)cc1n23)Sc4ccccc4
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Chemical Name8-Chloro-4-(phenylthio)-1-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Gururaja TL, et al. A class of small molecules that inhibit TNFalpha-induced survival and death pathways viaprevention of interactions between TNFalphaRI, TRADD, and RIP1. Chem Biol. 2007 Oct;14(10):1105-18.
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